Abiprubart
Based on 1 Customer Validation
Abiprubart is an anti-CD40 human IgG4 κ monoclonal antibody. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
For research use only. We do not sell to patients.
- Purity: 99.00%
- CAS No.: 2765071-95-0
- Molecular Weight:144.036 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG4 kappa
Human
CD40
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
P25942-1
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Human IgG4 kappa
ELISA, FACS, Functional assay
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Loaded CD40 Protein, Human (HEK293, His, HY-P73499A) on AHC2 biosensor, can bind Abiprubart with an affinity constant of 2.792E-09 M as determined in BLI assay. -
Flow Cytometry analysis of Raji cells labelling CD40 (red) with Abiprubart (anti-CD40) (HY-P990726). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG4 kappa (HY-P99003). Black-Unlabelled control, cells without incubation with primary antibody.
Chemical Information
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CAS No. 2765071-95-0
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Appearance Liquid
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Molecular Weight 144.036 kDa
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Color Colorless to light yellow
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Synonyms
KPL-404
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (253 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Abiprubart
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)