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Cat. No.: HY-153897

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PSB-1901

Name: PSB-1901
Brand: MedChemExpress
SKU: HY-153897
Price: 581.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

PSB-1901 is a potent A_2B adenosine receptor (A_2BAR) antagonist with K_is of 0.0835 nM and 0.131 nM for human and mouse A_2BARs respectively. PSB-1901 can be used for the research of cancer.

For research use only. We do not sell to patients.

Purity : 96.33%
CAS No.: 2332835-02-4
Formula: C₂₄H₂₅BrN₆O₄S
Molecular Weight:573.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PSB-1901 Chemical Structure

CAS No.: 2332835-02-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-103171
BAY 60-6583

A2B Receptor Agonist

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

PSB-1901 is a potent A_2B adenosine receptor (A_2BAR) antagonist with K_is of 0.0835 nM and 0.131 nM for human and mouse A_2BARs respectively. PSB-1901 can be used for the research of cancer^[1].

IC₅₀ & Target

Ki: 0.0835 nM (human A_2BAR), 0.131 nM (mouse A_2BAR)^[1]

All Adenosine Receptor Isoforms :

Chemical Information

CAS No. 2332835-02-4
Appearance Solid
Molecular Weight 573.46
Formula C₂₄H₂₅BrN₆O₄S
Color White to off-white
SMILES

O=C1NC2=C(C(N1CCC)=O)NC(C3=CC=C(S(=O)(N4CCN(CC4)C5=CC=C(C=C5)Br)=O)C=C3)=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (174.38 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.7438 mL

8.7190 mL

17.4380 mL

5 mM

0.3488 mL

1.7438 mL

3.4876 mL

10 mM

0.1744 mL

0.8719 mL

1.7438 mL

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jiang J, et al. A2B Adenosine Receptor Antagonists with Picomolar Potency. J Med Chem. 2019 Apr 25;62(8):4032-4055. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.7438 mL	8.7190 mL	17.4380 mL	43.5950 mL
	5 mM	0.3488 mL	1.7438 mL	3.4876 mL	8.7190 mL
	10 mM	0.1744 mL	0.8719 mL	1.7438 mL	4.3595 mL
	15 mM	0.1163 mL	0.5813 mL	1.1625 mL	2.9063 mL
	20 mM	0.0872 mL	0.4360 mL	0.8719 mL	2.1798 mL
	25 mM	0.0698 mL	0.3488 mL	0.6975 mL	1.7438 mL
	30 mM	0.0581 mL	0.2906 mL	0.5813 mL	1.4532 mL
	40 mM	0.0436 mL	0.2180 mL	0.4360 mL	1.0899 mL
	50 mM	0.0349 mL	0.1744 mL	0.3488 mL	0.8719 mL
	60 mM	0.0291 mL	0.1453 mL	0.2906 mL	0.7266 mL
	80 mM	0.0218 mL	0.1090 mL	0.2180 mL	0.5449 mL
	100 mM	0.0174 mL	0.0872 mL	0.1744 mL	0.4360 mL

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References

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MCE Japan Authorized Agent:

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PSB-1901

All Adenosine Receptor Isoforms

Biological Activity

Description

IC50 & Target

Chemical Information

Solvent & Solubility

In Vitro:

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

PSB-1901 Related Classifications

HY-153897 Related Classifications

Bioz

Keywords

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