JAK-IN-39
JAK-IN-39 (compound 11) is a JAK inhibitor that suppresses JAK1, JAK2, JAK3 with IC50 values of 0.05, 1.18, and 0.03 nM, respectively. JAK-IN-39 can inhibit the viability of TF-1 cells and also suppress the production of lymphocyte TNFα and INFγ in vitro.
For research use only. We do not sell to patients.
- CAS No.: 2250013-34-2
- Formula: C25H26N10O2
- Molecular Weight:498.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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JAK1 0.05 nM (IC50) |
JAK2 1.18 nM (IC50) |
JAK3 0.03 nM (IC50) |
Chemical Information
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CAS No. 2250013-34-2
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Molecular Weight 498.54
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Formula C25H26N10O2
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SMILES
COC1=NC(C2=NN3C(N[C@H]4C(C)(CN(C5=CC=C(N=N5)C#N)CC4)C)=C(C(N)=O)C=NC3=C2)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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