JNJ-40068782
JNJ-40068782 is a potent positive allosteric modulator of the mGlu2 receptor, with the IC50 of 38 nM.
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- CAS No.: 950196-50-6
- Formule: C21H23N3O
- Masse moléculaire:333.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
151 nM
Compound: 19
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Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins
Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 mins prior to [35S]GTPgamma addition measured after 30 mins
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[PMID: 25032784] |
Chemical Information
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CAS No. 950196-50-6
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Masse moléculaire 333.43
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Formule C21H23N3O
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SMILES
N#CC1=C(C=CN(C1=O)CC2CC2)N3CCC(CC3)C4=CC=CC=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JNJ-40068782 Related Classifications
HY-123433 Related Classifications
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