country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-16781S

Copy Link Print Information

Grapiprant-d₄

(Synonyms: CJ-023423-d₄; RQ-00000007-d₄; AAT-007-d₄)

Grapiprant-d₄ (CJ-023423-d₄) is the deuterium labeled Grapiprant (HY-16781). Grapiprant (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E₂ (PGE₂). Grapiprant displaces [³H]-PGE₂ (1 nM) binding to dog recombinant EP4 receptor with IC₅₀ value of 35 nM and K_i value of 24 nM. Grapiprant has the potential for osteoarthritic pain and inflammation treatment^[3].

For research use only. We do not sell to patients.

Formula: C₂₆H₂₅D₄N₅O₃S
Molecular Weight:495.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Grapiprant-d₄ Chemical Structure

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Prostaglandin Receptor Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 415903-37-6
Molecular Weight 495.63
Formula C₂₆H₂₅D₄N₅O₃S
SMILES

O=S(C1=CC=C(C)C=C1)(NC(NC([2H])([2H])C([2H])([2H])C2=CC=C(N3C(CC)=NC4=C3C=C(C)N=C4C)C=C2)=O)=O
Synonyms

CJ-023423-d₄; RQ-00000007-d₄; AAT-007-d₄
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.