HYF031
HYF031 is a selective, blood-brain barrier-permeable HDAC8 inhibitor with an IC50 of 5.7 nM, and exhibits extremely low activity against most other HDAC subtypes. HYF031 is applicable for HDAC8 imaging studies.
For research use only. We do not sell to patients.
- CAS No.: 1417997-91-1
- Formula: C16H14BrNO3
- Molecular Weight:348.19
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
HDAC8 5.7 nM (IC50) |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1417997-91-1
-
Molecular Weight 348.19
-
Formula C16H14BrNO3
-
SMILES
COC1=CC=C(C(C2=CC=C(C=C2)Br)=C1)/C=C/C(NO)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HYF031 Related Classifications
HY-183565 Related Classifications
Powered by Bioz