PRN-371
PRN-371 is a potent and selective JAK3 inhibitor. PRN371 effectively suppresses natural killer/T-cell lymphoma cell proliferation and induces apoptosis through abrogation of the JAK3-STAT signaling. PRN-371 exhibits antitumor activity and can be used for the research of cancer, such as hematological malignancies.
For research use only. We do not sell to patients.
- CAS No.: 1610974-55-4
- Formula: C20H21N5O2
- Molecular Weight:363.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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JAK3 |
Chemical Information
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CAS No. 1610974-55-4
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Molecular Weight 363.41
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Formula C20H21N5O2
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SMILES
O=C(C1=CNC2=NC=C(C3=CC=CC(NC(C=C)=O)=C3)N=C21)NC(C)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)