ARL 17477
Based on 1 publication(s) in Google Scholar
ARL-17477 is a dual inhibitor of NOS1and the autophagy-lysosomal system with anticancer activity and can inhibit tumor growth in KRAS-mutated cancers.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.02%
- CAS 番号: 866914-87-6
- 分子式: C20H22Cl3N3S
- 分子量:442.83
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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MedChemExpress（MCE）の使用を引用している文献 ARL 17477
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生物活性
化学情報
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CAS 番号 866914-87-6
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性状 Solid
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分子量 442.83
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分子式 C20H22Cl3N3S
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Color Off-white to light yellow
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SMILES
[H]Cl.[H]Cl.N=C(C1=CC=CS1)NC2=CC=C(CCNCC3=CC(Cl)=CC=C3)C=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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bioRxiv
Targeting GPR183 to reduce peripheral sensitization: evidence from rodent and human tissue analyses. [Abstract]2026 Jan 16:2026.01.15.699745. PMID: 41648147
溶剤 & 溶解度
DMSO : 62.5 mg/mL (141.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 20 mg/mL (45.16 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 2.2582 mL | 11.2910 mL | 22.5820 mL | 56.4551 mL |
| 5 mM | 0.4516 mL | 2.2582 mL | 4.5164 mL | 11.2910 mL | |
| 10 mM | 0.2258 mL | 1.1291 mL | 2.2582 mL | 5.6455 mL | |
| 15 mM | 0.1505 mL | 0.7527 mL | 1.5055 mL | 3.7637 mL | |
| 20 mM | 0.1129 mL | 0.5646 mL | 1.1291 mL | 2.8228 mL | |
| 25 mM | 0.0903 mL | 0.4516 mL | 0.9033 mL | 2.2582 mL | |
| 30 mM | 0.0753 mL | 0.3764 mL | 0.7527 mL | 1.8818 mL | |
| 40 mM | 0.0565 mL | 0.2823 mL | 0.5646 mL | 1.4114 mL | |
| DMSO | 50 mM | 0.0452 mL | 0.2258 mL | 0.4516 mL | 1.1291 mL |
| 60 mM | 0.0376 mL | 0.1882 mL | 0.3764 mL | 0.9409 mL | |
| 80 mM | 0.0282 mL | 0.1411 mL | 0.2823 mL | 0.7057 mL | |
| 100 mM | 0.0226 mL | 0.1129 mL | 0.2258 mL | 0.5646 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
ARL 17477 関連分類
HY-107720 関連分類
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