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製品番号: HY-P11646

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Brazzein

Name: Brazzein
Brand: MedChemExpress
SKU: HY-P11646
Availability: PreOrder

Brazzein is a functional sweetener with antioxidant, anti-inflammatory, and anti-allergic activities.

Brazzein inhibits COX-2 with an IC₅₀ of 12.62 μM. Brazzein exhibits strong antioxidant effects, showing ABTS radical scavenging activity (IC₅₀ = 12.55 μM). Brazzein shows no antibacterial or antifungal activity. Brazzein can be used for the research of obesity, metabolic disorder, inflammation.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 178359-31-4
分子式: C₂₇₆H₄₁₀N₇₆O₈₉S₈
分子量:6473.18

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Brazzein 構造式

CAS 番号: 178359-31-4

容量

価格（税別）

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Brazzein is a functional sweetener with antioxidant, anti-inflammatory, and anti-allergic activities.

IC₅₀ & Target^[1]

COX-2

12.62 μM (IC₅₀)

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体外実験

Brazzein (15-30 μM) shows strong ABTS radical scavenging activity with an IC₅₀ of 12.55 μM in cell-free conditions^[1].
Brazzein (15-30 μM; 30 min) shows weaker DPPH radical scavenging activity compared to ABTS, with an IC₅₀ > 30 μM in cell-free conditions^[1].
Brazzein (3-25 μM) inhibits human COX-2 activity with an IC₅₀ of 12.62 μM in cell-free conditions^[1].
Brazzein (1–15 μM) shows weak anti-inflammatory activity in RAW 264.7 cells, with an IC₅₀ > 15 μM for NO production inhibition^[1].
Brazzein (1-15 μM) has no cytotoxic effect on RAW 264.7 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 178359-31-4
分子量 6473.18
分子式 C₂₇₆H₄₁₀N₇₆O₈₉S₈
配列

Glp-Asp-Lys-Cys-Lys-Lys-Val-Tyr-Glu-Asn-Tyr-Pro-Val-Ser-Lys-Cys-Gln-Leu-Ala-Asn-Gln-Cys-Asn-Tyr-Asp-Cys-Lys-Leu-Asp-Lys-His-Ala-Arg-Ser-Gly-Glu-Cys-Phe-Tyr-Asp-Glu-Lys-Arg-Asn-Leu-Gln-Cys-Ile-Cys-Asp-Tyr-Cys-Glu-Tyr (disulfide bridge:Cys4-Cys52,Cys16-Cys37,Cys22-Cys47,Cys26-Cys49)
シーケンスの短縮

Glp-DKCKKVYENYPVSKCQLANQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY (disulfide bridge:Cys4-Cys52,Cys16-Cys37,Cys22-Cys47,Cys26-Cys49)
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (264 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Chung JH, et al. Antioxidant, anti-inflammatory, and anti-allergic activities of the sweet-tasting protein brazzein. Food Chem. 2018;267:163-169. [Content Brief]

[2]. Martinez Raquel, et al. Brazzein as a sustainable alternative to sugar: production, perception, and public health impact. J Appl Biotechnol Bioeng. 2025;12(1):45-48.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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生物活性
- 製品説明
- IC₅₀ & Target
- 体外実験
化学情報
純度とドキュメンテーション
参考文献

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Brazzein

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