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製品番号: HY-N7423A

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(E)-Methyl isoferulate

Name: (E)-Methyl isoferulate
Brand: MedChemExpress
SKU: HY-N7423A
Availability: PreOrder

(別名: (E)-Isoferulic acid methyl ester)

(E)-Methyl isoferulate ((E)-Isoferulic acid methyl ester) is a derivative of Cinnamic acid (HY-N0610A) and NO inhibitor, with an IC₅₀ > 100 μM against nitric oxide production. (E)-Methyl isoferulate is isolable from the solid cultures of the edible mushroom Neolentinus lepideus. (E)-Methyl isoferulate exerts mild anticancer effects against liver cancer and leukemia.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 97966-29-5
分子式: C₁₁H₁₂O₄
分子量:208.21

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

(E)-Methyl isoferulate 構造式

CAS 番号: 97966-29-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
- 体外実験
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
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生物活性

製品説明

IC₅₀ & Target

^[1]

Fungal Metabolite

NO Synthase アイソフォーム固有の製品をすべて表示 :

Endogenous Metabolite アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
A-431	IC₅₀	30 μg/mL Compound: 4i	Inhibitory concentration required against A 431 human epidermoid carcinoma cell line Inhibitory concentration required against A 431 human epidermoid carcinoma cell line	[PMID: 11354370]
B16	IC₅₀	25.88 μg/mL Compound: 4i	Inhibitory concentration against B16 murine melanoma cell line Inhibitory concentration against B16 murine melanoma cell line	[PMID: 11354370]
HCT-116	IC₅₀	27.49 μg/mL Compound: 4i	Inhibitory concentration against HCT 116 human colon cancer cell line Inhibitory concentration against HCT 116 human colon cancer cell line	[PMID: 11354370]

体外実験

(E)-Methyl isoferulate (Compound 8) (3.125-100 μM; 24 h) weakly inhibits LPS-induced nitric oxide production in RAW 264.7 cells, with an IC₅₀ greater than 100 μM, and shows no cytotoxicity to these cells at 100 μM^[1].
(E)-Methyl isoferulate (72 h) displays weak cytotoxicity against HepG2 and K562 cells, with an IC₅₀ greater than 200 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Liver Cancer Modeling

化学情報

CAS 番号 97966-29-5
分子量 208.21
分子式 C₁₁H₁₂O₄
SMILES

COC(/C=C/C1=CC(O)=C(C=C1)OC)=O
別名

(E)-Isoferulic acid methyl ester
Structure Classification
- Phenylpropanoids
- Simple Phenylpropanols
- Phenols
- Monophenols
Initial Source
- Microorganism
Neolentinus lepideus
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Li Y, et al. A new benzoquinone and a new benzofuran from the edible mushroom Neolentinus lepideus and their inhibitory activity in NO production inhibition assay. Food Chem. 2013;141(3):1614-1618. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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希釈計算機

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濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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