F3 peptide
F3 peptide is a fragment of the human high mobility group protein 2 (HMGB2), and can specifically bind to nucleolin expressed on the membrane of cancer cells, neovasculature, and endothelium. F3 peptide can be used as an effective ligand to improve their druggability of macromolecular drugs or nanoparticles, and so on.
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- CAS 番号: 536971-53-6
- 分子式: C152H263N49O41
- 分子量:3433.02
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 536971-53-6
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分子量 3433.02
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分子式 C152H263N49O41
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配列
Lys-Asp-Glu-Pro-Gln-Arg-Arg-Ser-Ala-Arg-Leu-Ser-Ala-Lys-Pro-Ala-Pro-Pro-Lys-Pro-Glu-Pro-Lys-Pro-Lys-Lys-Ala-Pro-Ala-Lys-Lys
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シーケンスの短縮
KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Hu Q, et al. F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery. Biomaterials. 2013 Jan;34(4):1135-45. [Content Brief]
[2]. Ham SH, et al. Molecular tumor targeting of gelonin by fusion with F3 peptide. Acta Pharmacol Sin. 2017 Jun;38(6):897-906. [Content Brief]
[3]. Tao Z, et al. Multivalent assembly of nucleolin-targeted F3 peptide potentiates TRAIL's tumor penetration and antitumor effects. J Control Release. 2025 Jul 10;383:113835. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)