Idroxioleic acid
Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 182370-45-2
- 分子式: C18H34O3
- 分子量:298.46
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) inhibited the growth of A549, lung adenocarcinoma cell line with an IC50 of 252 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male NUDE (Swiss) Crl:NU(Ico)-Foxn1nu mice (5 weeks old, 30-35 g) injected with A549 human lung cancer cells[1]
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Dosage:400 mg/kg
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Administration:p.o.; daily; for 21 days
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Result:Caused a reduction in tumor volume of about 20-25% after 21 days.
化学情報
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CAS 番号 182370-45-2
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分子量 298.46
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分子式 C18H34O3
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SMILES
OC([C@H](O)CCCCCC/C=C\CCCCCCCC)=O
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別名
(R)-2-Hydroxyoleic acid; (R)-2-OHOA; (R)-LAM561
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)