JAK2-IN-4
JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1438284-00-4
- 分子式: C23H27N5O4S
- 分子量:469.56
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
製品説明
IC50 & Target
IC50: 0.7 nM/23.2 nM (JAK2/JAK3)[1].
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEL | IC50 |
1254 nM
Compound: 16h
|
Inhibition of JAK2 V617F mutant in human HEL cells after 1 hr
Inhibition of JAK2 V617F mutant in human HEL cells after 1 hr
|
[PMID: 27771180] |
| TF-1 | IC50 |
425.6 nM
Compound: 16h
|
Inhibition of JAK2 in human TF1 cells assessed as suppression of cell growth
Inhibition of JAK2 in human TF1 cells assessed as suppression of cell growth
|
[PMID: 27771180] |
化学情報
-
CAS 番号 1438284-00-4
-
分子量 469.56
-
分子式 C23H27N5O4S
-
SMILES
CC(C=NC(NC1=CC=C(N2CCOCC2)C=C1)=N3)=C3C(O4)=CC5=C4CCN(S(=O)(C)=O)C5
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
JAK2-IN-4 関連分類
HY-100759 関連分類
Powered by Bioz