L-783483
L-783483 (F3MethylAA) is an agonist for PPARδ. L-783483 ameliorates Carrageenan (HY-125474)-induced paw edema in mice.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 194608-77-0
- 分子式: C22H21ClF3NO4S
- 分子量:487.92
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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PPARδ |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
5900 nM
Compound: 1
|
Activity at LXR alpha as beta-lactamase transactivation in CHO cells
Activity at LXR alpha as beta-lactamase transactivation in CHO cells
|
[PMID: 16529931] |
| CHO | EC50 |
7300 nM
Compound: 1
|
Activity at LXR beta as beta-lactamase transactivation in CHO cells
Activity at LXR beta as beta-lactamase transactivation in CHO cells
|
[PMID: 16529931] |
| HEK293 | EC50 |
1080 nM
Compound: 1
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Effective concentration against liver X receptor-beta in HEK293 cell transactivation assay
Effective concentration against liver X receptor-beta in HEK293 cell transactivation assay
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[PMID: 15911262] |
| HEK293 | EC50 |
1790 nM
Compound: 1
|
Effective concentration against liver X receptor-alpha in HEK293 cell transactivation assay
Effective concentration against liver X receptor-alpha in HEK293 cell transactivation assay
|
[PMID: 15911262] |
化学情報
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CAS 番号 194608-77-0
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分子量 487.92
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分子式 C22H21ClF3NO4S
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SMILES
O=C(CC1=CC=C(C(Cl)=C1)SCCCOC2=C(CCC)C(ON=C3C(F)(F)F)=C3C=C2)O
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別名
F3MethylAA
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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