L07-2
Based on 1 Customer Validation
L07-2 is a TLR7/8 agonist. L07-2 is a linker-toxin building block that can be used to synthesize immunostimulatory antibody conjugates (ISACs) for cancer research. L07-2 can be used to studies related to tumors such as non-small cell lung cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.83%
- CAS 番号: 3093296-36-4
- 分子式: C56H83N15O14
- 分子量:1190.35
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保管条件:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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TLR7 |
TLR8 |
L07-2 (compound 6) (6 h) acts as a potent TLR7/8 dual agonist that activates NF-κB signaling in H-TLR7 and H-TLR8 reporter 293 cells, with stronger TLR7 activity than Resiquimod (R848)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3093296-36-4
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性状 Solid
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分子量 1190.35
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分子式 C56H83N15O14
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Color White to off-white
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SMILES
O=C(C=C1)N(CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N(C)CC(N[C@@H](CC(C)(C)C)C(NCCOC(C)(C)CN2C(COCC)=NC3=C2C4=C(C=CC=C4)N=C3N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C1=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (84.01 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8401 mL | 4.2004 mL | 8.4009 mL | 21.0022 mL |
| 5 mM | 0.1680 mL | 0.8401 mL | 1.6802 mL | 4.2004 mL | |
| 10 mM | 0.0840 mL | 0.4200 mL | 0.8401 mL | 2.1002 mL | |
| 15 mM | 0.0560 mL | 0.2800 mL | 0.5601 mL | 1.4001 mL | |
| 20 mM | 0.0420 mL | 0.2100 mL | 0.4200 mL | 1.0501 mL | |
| 25 mM | 0.0336 mL | 0.1680 mL | 0.3360 mL | 0.8401 mL | |
| 30 mM | 0.0280 mL | 0.1400 mL | 0.2800 mL | 0.7001 mL | |
| 40 mM | 0.0210 mL | 0.1050 mL | 0.2100 mL | 0.5251 mL | |
| 50 mM | 0.0168 mL | 0.0840 mL | 0.1680 mL | 0.4200 mL | |
| 60 mM | 0.0140 mL | 0.0700 mL | 0.1400 mL | 0.3500 mL | |
| 80 mM | 0.0105 mL | 0.0525 mL | 0.1050 mL | 0.2625 mL |
L07-2 関連分類
HY-176774 関連分類
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