MMAF-methyl ester
MMAF-methyl ester is a methylated derivative of the tubulin inhibitor MMAF (HY-15579), and serves as a pharmaceutical intermediate for the development of antibody-drug conjugates (ADCs) and small-molecule drug conjugates (SMDCs).
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- CAS 番号: 2353409-70-6
- 分子式: C40H67N5O8
- 分子量:745.99
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
MMAF is a potent tubulin polymerization inhibitor that is widely used as the cytotoxic component of antibody-drug conjugates (ADCs), such as Vorsetuzumab mafodotin (HY-P99334).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2353409-70-6
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分子量 745.99
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分子式 C40H67N5O8
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SMILES
COC([C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(CC(OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@@H](NC)C(C)C)=O)=O)=O)OC)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)