MTT5
Based on 1 Customer Validation
MTT5 is a toll-like receptor 7 (TLR7) agonist. MTT5 can couple with Deruxtecan (HY-13631E) and exert anti-tumor activity in HER2 positive solid tumors through tumor cell killing and immune activation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.49%
- 分子式: C22H27N7O4
- 分子量:453.49
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
IC50 & Target
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TLR7 |
化学情報
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性状 Solid
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分子量 453.49
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分子式 C22H27N7O4
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Color White to off-white
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SMILES
COCCOC1=NC(N)=C2NC(N(C2=N1)CC3=CC=C(C=C3)C(N4CC5CNCC5C4)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 25 mg/mL (55.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2051 mL | 11.0256 mL | 22.0512 mL | 55.1280 mL |
| 5 mM | 0.4410 mL | 2.2051 mL | 4.4102 mL | 11.0256 mL | |
| 10 mM | 0.2205 mL | 1.1026 mL | 2.2051 mL | 5.5128 mL | |
| 15 mM | 0.1470 mL | 0.7350 mL | 1.4701 mL | 3.6752 mL | |
| 20 mM | 0.1103 mL | 0.5513 mL | 1.1026 mL | 2.7564 mL | |
| 25 mM | 0.0882 mL | 0.4410 mL | 0.8820 mL | 2.2051 mL | |
| 30 mM | 0.0735 mL | 0.3675 mL | 0.7350 mL | 1.8376 mL | |
| 40 mM | 0.0551 mL | 0.2756 mL | 0.5513 mL | 1.3782 mL | |
| 50 mM | 0.0441 mL | 0.2205 mL | 0.4410 mL | 1.1026 mL |