NIR‐fluorescent glucose
NIR-fluorescent glucose is a functional glucose-based fluorescent imaging agent. Conjugated with the nitrobenzoselenadiazole-based SCOTfluor (compound 9), NIR-fluorescent glucose acts as a substrate for GLUT4 and GLUT2 transporters. NIR-fluorescent glucose enables the visualization of glucose uptake in live cells and in vivo.
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- CAS 番号: 2364376-61-2
- 分子式: C12H14N4O7Se
- 分子量:405.22
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
[1]|
GLUT2 |
GLUT4 |
体外実験
The NIR-fluorescent glucose (100 μM) is a functional substrate of GLUT4 in GLUT4-EGFP HeLa cells, with measurable uptake that is competitively inhibited by excess glucose and enhanced by insulin pre-treatment[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2364376-61-2
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分子量 405.22
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分子式 C12H14N4O7Se
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SMILES
OC[C@H]1O[C@@H](O)[C@H](NC2=CC=C([N+]([O-])=O)C3=N[Se]N=C32)[C@@H](O)[C@@H]1O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)