p21PBP
p21PBP, a 20 amino-acid peptide, is an inhibitor of DNA replication. p21PBP specifically binds to purified proliferating cell nuclear antigen (PCNA) in tumour cell extracts. p21PBP is promising for research of cancers.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C112H181N37O30S
- 分子量:2557.93
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
化学情報
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分子量 2557.93
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分子式 C112H181N37O30S
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配列
Gln-Asp-Lys-Thr-Arg-Tyr-Phe-His-Arg-Thr-Met-Ser-Arg-Ser-Lys-Ser-Ile-Arg-Leu-Phe
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シーケンスの短縮
QDKTRYFHRTMSRSKSIRLF
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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PCNA Immunodetection Proliferation Assay
PCNA immunodetection measures proliferative activity by detecting proliferating cell nuclear antigen, a nuclear protein associated with DNA polymerase δ function and DNA replication. The assay readout is the proportion of PCNA-positive nuclei among total counted cells, but PCNA labeling is not identical to BrdU labeling because PCNA can mark late G1/early S-associated replication competence and may persist beyond active DNA synthesis depending on fixation and extraction conditions.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)