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PBD dimer-4

PBD dimer-4 (Compound 7) is a C1-subsitituted PBD dimer. PBD dimer-4 has high DNA-binding affinity, DNA cross-linking ability and potent cytotoxicity against MDA-MB-231 cells (IC50: 236 nM). PBD dimer-4 can be used as a payload of ADC Loncastuximab tesirine (HY-P99349) to treat several different cancer types.

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  • CAS 番号: 1821339-88-1
  • 分子式: C31H36N4O8
  • 分子量:592.64
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • PBD dimer-4 Chemical Structure
    PBD dimer-4 構造式
CAS 番号: 1821339-88-1
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  • PBD dimer-4 Chemical Structure
    PBD dimer-4 Chemical Structure
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  • PBD dimer-4