Phaseic acid
Based on 1 publication(s) in Google Scholar
Phaseic acid is a Abscisic acid terpenoid catabolite that can able to activate a subset of Abscisic acid repectors. Phaseic acid is a plant hormone associated with photosynthesis arrest and abscission. Phaseic acid is the antagonist for NMDA-type glutamate receptor (NMDAR) that inhibits NMDAR currents with an IC50 of 34.37 μM. Phaseic acid reduces intracellular calcium influx, and exhibits neuroprotective effect.
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- 純度: 98.76%
- CAS 番号: 24394-14-7
- 分子式: C15H20O5
- 分子量:280.32
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Phaseic acid
MorePhytohormone アイソフォーム固有の製品をすべて表示
MoreiGluR アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
>10 μM
Compound: 21
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Antiinflammatory activity in C57BL6/J mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in C57BL6/J mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
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[PMID: 26110443] |
| MDCK | IC50 |
>35 μM
Compound: 21
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Antiviral activity against Influenza A virus (A/FM/1/47(H1N1)) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect
Antiviral activity against Influenza A virus (A/FM/1/47(H1N1)) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect
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[PMID: 26110443] |
| Vero | IC50 |
>35 μM
Compound: 21
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Antiviral activity against Coxsackievirus B3 infected in African green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect
Antiviral activity against Coxsackievirus B3 infected in African green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect
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[PMID: 26110443] |
Phaseic acid (10 µM, 3 h) promotes the stomatal closure, reduces water evaporation in Commelina communis leaves[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mouse cerebral artery occlusion (MCAO) models[2]
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Dosage:50 mg/mL
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Administration:intraventricular injection, continuous infusion for 3 days
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Result:Reduced the volume of ischemic brain lesions.
化学情報
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CAS 番号 24394-14-7
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性状 Solid
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分子量 280.32
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分子式 C15H20O5
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Color White to off-white
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SMILES
O=C(O)/C=C(C)\C=C\[C@]1(O)[C@]2(C)CC(C[C@@]1(C)OC2)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Agric Food Chem
Development of an Ultrahigh-Performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry Method for Multiclass Phytohormone Quantification Via Multifunctional Chemical Derivatization. [Abstract]2026 May 27;74(20):15910-15920. PMID: 42145237
純度とドキュメンテーション
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データシート (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Pedro L Rodriguez, et al. Abscisic Acid Catabolism Generates Phaseic Acid, a Molecule Able to Activate a Subset of ABA Receptors. Mol Plant. 2016 Nov 7;9(11):1448-1450. [Content Brief]
[2]. Hou ST, et al., Phaseic Acid, an Endogenous and Reversible Inhibitor of Glutamate Receptors in Mouse Brain. J Biol Chem. 2016 Dec 30;291(53):27007-27022. [Content Brief]
[3]. Sharkey TD, et al., Effects of phaseic Acid and dihydrophaseic Acid on stomata and the photosynthetic apparatus. Plant Physiol. 1980 Feb;65(2):291-7. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Phaseic acid 関連分類
HY-111973 関連分類
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