PY109
Based on 1 Customer Validation
PY109 is an orally active and highly selective aryl hydrocarbon receptor (AHR) agonist. PY109's EC50 values in human-derived HepG2 and mouse Hepa-1c1c7 cells are 1.2 nM and 1.4 nM respectively. PY109 significantly upregulates the expression of CYP1A1 and IL-22, and inhibits the expression of IL-17A. PY109 significantly improves colitis in mice. PY109 can be used for research on colitis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.15%
- CAS 番号: 2378039-23-5
- 分子式: C15H9F3N2O
- 分子量:290.24
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
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Help & FAQs
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生物活性
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CYP1A1 |
IL-22 |
IL-17A |
化学情報
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CAS 番号 2378039-23-5
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性状 Solid
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分子量 290.24
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分子式 C15H9F3N2O
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Color Off-white to light yellow
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SMILES
O=C(C1=CNC2=C1C=CC=C2)C3=NC(C(F)(F)F)=CC=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (344.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (252 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4454 mL | 17.2271 mL | 34.4542 mL | 86.1356 mL |
| 5 mM | 0.6891 mL | 3.4454 mL | 6.8908 mL | 17.2271 mL | |
| 10 mM | 0.3445 mL | 1.7227 mL | 3.4454 mL | 8.6136 mL | |
| 15 mM | 0.2297 mL | 1.1485 mL | 2.2969 mL | 5.7424 mL | |
| 20 mM | 0.1723 mL | 0.8614 mL | 1.7227 mL | 4.3068 mL | |
| 25 mM | 0.1378 mL | 0.6891 mL | 1.3782 mL | 3.4454 mL | |
| 30 mM | 0.1148 mL | 0.5742 mL | 1.1485 mL | 2.8712 mL | |
| 40 mM | 0.0861 mL | 0.4307 mL | 0.8614 mL | 2.1534 mL | |
| 50 mM | 0.0689 mL | 0.3445 mL | 0.6891 mL | 1.7227 mL | |
| 60 mM | 0.0574 mL | 0.2871 mL | 0.5742 mL | 1.4356 mL | |
| 80 mM | 0.0431 mL | 0.2153 mL | 0.4307 mL | 1.0767 mL | |
| 100 mM | 0.0345 mL | 0.1723 mL | 0.3445 mL | 0.8614 mL |
PY109 関連分類
HY-147128 関連分類
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