Quinethazone
Quinethazone is an orally active diuretic agent and is also a weak inhibitor of carbonic anhydrase. Quinethazone can be used for hypertension research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 73-49-4
- 分子式: C10H12ClN3O3S
- 分子量:289.74
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Five- to 6-week-old Long Evans male rats, hypertension model[1]
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Dosage:50 mg/kg
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Administration:Oral, daily for 2 weeks
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Result:Had no significant effect on sodium or water distribution in arterial tissue of hypertensive rats, but decreased approximate 20% intra-cellular content of potassium
化学情報
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CAS 番号 73-49-4
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性状 Solid
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分子量 289.74
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分子式 C10H12ClN3O3S
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Color Light brown to brown
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SMILES
O=S(C1=CC2=C(NC(CC)NC2=O)C=C1Cl)(N)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. FREED SC. MECHANISM OF ANTI-HYPERTENSIVE ACTION OF QUINETHAZONE. Proc Soc Exp Biol Med. 1963 Nov;114:421-2. [Content Brief]
[2]. Angelopoulos B, et al. Experimental investigation and observations on the diuretic action of quinethazone. Med Pharmacol Exp Int J Exp Med. 1966;14(6):528-36. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Quinethazone 関連分類
HY-B1364 関連分類
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