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(R)-Vorbipiprant

(別名: (R)-CR6086)

(R)-Vorbipiprant ((R)-CR6086) is an orally active antagonist for prostaglandin E2 receptor 4 (EP4) with Ki of 16.6 nM for human EP4. (R)-Vorbipiprant inhibits PGE2 (HY-101952)-induced cAMP production with an IC50 of 22 nM. (R)-Vorbipiprant exhibits immunomodulatory and anti-angiogenic activities, and ameliorates the collagen-induced arthritis in mice.

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  • CAS 番号: 2502965-92-4
  • 分子式: C26H27F3N2O3
  • 分子量:472.50
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • (R)-Vorbipiprant Chemical Structure
    (R)-Vorbipiprant 構造式
CAS 番号: 2502965-92-4
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最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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  • (R)-Vorbipiprant Chemical Structure
    (R)-Vorbipiprant Chemical Structure
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  • (R)-Vorbipiprant