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(Rac)-BDA-366

(Rac)-BDA-366 (example 2) is the despinner of BDA-366 (HY-101083). BDA-366 is a potent Bcl-2 antagonist (Ki=3.3 nM), binding Bcl-2-BH4 domain with high affinity and selectivity. BDA-366 induces conformational change in Bcl-2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells.

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  • CAS 番号: 142645-19-0
  • 分子式: C24H29N3O4
  • 分子量:423.50
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • (Rac)-BDA-366 Chemical Structure
    (Rac)-BDA-366 構造式
CAS 番号: 142645-19-0
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  • (Rac)-BDA-366 Chemical Structure
    (Rac)-BDA-366 Chemical Structure
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  • (Rac)-BDA-366