(S)-3,4-DCPG
Based on 1 Customer Validation
(S)-3,4-DCPG is a selective agonist of metabotropic glutamate receptor 8a (mGluR8a) with an EC50 of 31 nM in AV12-664 cells expressing human mGluR8.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98%
- CAS 番号: 201730-11-2
- 分子式: C10H9NO6
- 分子量:239.18
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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hmGluR8a 31 nM (EC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
<100 μM
Compound: 10
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Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Active
Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Active
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[PMID: 15801843] |
| HEK293 | EC50 |
8.8 μM
Compound: 10
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Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells
Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells
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[PMID: 15801843] |
化学情報
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CAS 番号 201730-11-2
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性状 Solid
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分子量 239.18
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分子式 C10H9NO6
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Color White to light yellow
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SMILES
OC(C1=C(C=CC([C@H](N)C(O)=O)=C1)C(O)=O)=O
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別名
(S)-3,4-Dicarboxyphenylglycine
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 20 mg/mL (83.62 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (393 KB)
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- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1810 mL | 20.9048 mL | 41.8095 mL | 104.5238 mL |
| 5 mM | 0.8362 mL | 4.1810 mL | 8.3619 mL | 20.9048 mL | |
| 10 mM | 0.4181 mL | 2.0905 mL | 4.1810 mL | 10.4524 mL | |
| 15 mM | 0.2787 mL | 1.3937 mL | 2.7873 mL | 6.9683 mL | |
| 20 mM | 0.2090 mL | 1.0452 mL | 2.0905 mL | 5.2262 mL | |
| 25 mM | 0.1672 mL | 0.8362 mL | 1.6724 mL | 4.1810 mL | |
| 30 mM | 0.1394 mL | 0.6968 mL | 1.3937 mL | 3.4841 mL | |
| 40 mM | 0.1045 mL | 0.5226 mL | 1.0452 mL | 2.6131 mL | |
| 50 mM | 0.0836 mL | 0.4181 mL | 0.8362 mL | 2.0905 mL | |
| 60 mM | 0.0697 mL | 0.3484 mL | 0.6968 mL | 1.7421 mL | |
| 80 mM | 0.0523 mL | 0.2613 mL | 0.5226 mL | 1.3065 mL |
(S)-3,4-DCPG 関連分類
HY-107516 関連分類
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