B-Raf IN 19
B-Raf IN 19 (compound 31) is a BRAF inhibitor that inhibits BRAF(WT) and BRAF(V600E) (IC50: 0.57 μM and 0.28 μM, respectively). B-Raf IN 19 inhibits MAPK signaling in melanoma cells.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 708218-62-6
- 分子式: C20H15NO3S3
- 分子量:413.53
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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BRAFWT 0.57 μM (IC50) |
BRafV600E 0.28 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
0.28 μM
Compound: 31
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Inhibition of human 6x-His tagged BRAF V600E mutant expressed in Sf9 cells by ELISA based kinase assay
Inhibition of human 6x-His tagged BRAF V600E mutant expressed in Sf9 cells by ELISA based kinase assay
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[PMID: 22537109] |
| Sf9 | IC50 |
0.57 μM
Compound: 31
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Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assay
Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assay
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[PMID: 22537109] |
化学情報
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CAS 番号 708218-62-6
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分子量 413.53
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分子式 C20H15NO3S3
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SMILES
O=S(NC1=CC(SC2=CC=CC=C2)=C(C3=C1C=CC=C3)O)(C4=CC=CS4)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
B-Raf IN 19 関連分類
HY-155942 関連分類
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