UDP-Galactose
Based on 5 publication(s) in Google Scholar
UDP-Galactose is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose is the natural agonist of the P2Y14 receptor coupled to Gi proteins in the immune system (IC50 = 0.67 μM, hP2Y14). UDP-Galactose can be used to study cell signal transduction and substance metabolism.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2956-16-3
- 分子式: C15H24N2O17P2
- 分子量:566.30
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 UDP-Galactose
MoreEndogenous Metabolite アイソフォーム固有の製品をすべて表示
MoreP2Y Receptor アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
IC50 & Target
|
Human Endogenous Metabolite |
P2Y14 Receptor 0.67 μM (EC50) |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| COS-7 | EC50 |
0.67 μM
Compound: 2
|
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysis
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysis
|
[PMID: 17407275] |
| COS-7 | EC50 |
0.67 μM
Compound: 7
|
Agonist activity at human P2Y14 receptor expressed in human COS7 cells
Agonist activity at human P2Y14 receptor expressed in human COS7 cells
|
[PMID: 19502066] |
体外実験
UDP-Galactose (2 mM) restores UDP-galactose transport in the endoplasmic reticulum of GalT-1/UGT-CHOlec8 cells[2].
UDP-galactose is transported via the endoplasmic reticulum to support GalCer synthesis in GalT-1/UGT-CHOlec8 cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 2956-16-3
-
分子量 566.30
-
分子式 C15H24N2O17P2
-
SMILES
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[C@@H]3[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)(O)=O)(O)=O)O2)NC1=O
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (5)
-
Journal Impact Factor
-
Most Recent
-
Mol Plant
2025 Dec 13:S1674-2052(25)00435-6. PMID: 41392480 -
Cell Rep
Blocking glycogen synthase 1 in white adipose tissue alleviates hypermetabolism following severe burn injury through inhibition of JAK2 by UDPG. [Abstract]2025 Nov 18;44(12):116577. PMID: 41259203 -
J Exp Bot
Diel carbon buffering by floridoside enables source-sink resilience in the intertidal red alga Pyropia haitanensis. [Abstract]2026 Apr 17:erag189. PMID: 41999048 -
J Biotechnol
Rational design of a bifunctional glycosyltransferase for enhanced substrate promiscuity and thermostability. [Abstract]2025 Dec 19:410:285-297. PMID: 41422993 -
純度とドキュメンテーション
参考文献
[1].
Ko H, et al. Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J Med Chem. 2007 May 3;50(9):2030-9.
[Content Brief]
[2]. Sprong H, et al. Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum. Mol Biol Cell. 2003;14(8):3482-3493. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
UDP-Galactose 関連分類
HY-150524 関連分類
Powered by Bioz