Urethane-d5
Based on 1 Customer Validation
Urethane-d5 is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.5%
- CAS 番号: 73962-07-9
- 分子式: C3H2D5NO2
- 分子量:94.12
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 73962-07-9
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非標識Cas 51-79-6
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性状 Solid
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分子量 94.12
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分子式 C3H2D5NO2
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Color White to light brown
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SMILES
NC(OC([2H])([2H])C([2H])([2H])[2H])=O
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別名
Ethyl carbamate-d5; Carbamic acid ethyl ester-d5; Ethylurethane-d5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (1062.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
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- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. K J Field, et al. Hazards of urethane (ethyl carbamate): a review of the literature. Lab Anim. 1988 Jul;22(3):255-62.;R E Sotomayor, et al. Mutagenicity, metabolism, and DNA interactions of urethane. Toxicol Ind Health. 1990 Jan;6(1):71-108. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 10.6247 mL | 53.1237 mL | 106.2473 mL | 265.6184 mL |
| 5 mM | 2.1249 mL | 10.6247 mL | 21.2495 mL | 53.1237 mL | |
| 10 mM | 1.0625 mL | 5.3124 mL | 10.6247 mL | 26.5618 mL | |
| 15 mM | 0.7083 mL | 3.5416 mL | 7.0832 mL | 17.7079 mL | |
| 20 mM | 0.5312 mL | 2.6562 mL | 5.3124 mL | 13.2809 mL | |
| 25 mM | 0.4250 mL | 2.1249 mL | 4.2499 mL | 10.6247 mL | |
| 30 mM | 0.3542 mL | 1.7708 mL | 3.5416 mL | 8.8539 mL | |
| 40 mM | 0.2656 mL | 1.3281 mL | 2.6562 mL | 6.6405 mL | |
| 50 mM | 0.2125 mL | 1.0625 mL | 2.1249 mL | 5.3124 mL | |
| 60 mM | 0.1771 mL | 0.8854 mL | 1.7708 mL | 4.4270 mL | |
| 80 mM | 0.1328 mL | 0.6640 mL | 1.3281 mL | 3.3202 mL | |
| 100 mM | 0.1062 mL | 0.5312 mL | 1.0625 mL | 2.6562 mL |