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Vilobelimab

(別名: CaCP-29, IFX-1)
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Based on 1 Customer Validation

Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 99.27%
  • CAS 番号: 2250440-41-4
  • 分子量:145.88 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vilobelimab
  • Experimental Validation Results for Vilobelimab
  • Experimental Validation Results for Vilobelimab
  • Vilobelimab Chemical Structure
    Vilobelimab 構造式
CAS 番号: 2250440-41-4
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Vilobelimab おすすめ製品:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized Complement C5/C5a Protein, Human, HY-P7864) can bind Vilobelimab. The EC50 for this effect is 14.20 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 HepG2 cells labeling Vilobelimab (HY-P99520, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/50 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Vilobelimab Chemical Structure
    1/16
  • Vilobelimab
  • Immobilized Complement C5/C5a Protein, Human, HY-P7864) can bind Vilobelimab. The EC50 for this effect is 14.20 ng/mL.
  • Flow cytometric analysis of 1X106 HepG2 cells labeling Vilobelimab (HY-P99520, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/50 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).