WHN-88
WHN-88 is a Porcupine (PORCN) inhibitor. WHN-88 can eliminate the palmitoylation of Wnt ligands, preventing their secretion and subsequent Wnt/β-catenin signaling. WHN-88 can inhibit cancer cell stemness and suppress the occurrence and development of breast tumors in MMTV-Wnt1 transgenic mice.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2490686-86-5
- 分子式: C18H13I2N3O2
- 分子量:557.12
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
製品説明
化学情報
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CAS 番号 2490686-86-5
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分子量 557.12
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分子式 C18H13I2N3O2
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SMILES
O=C(CN1C=C(I)C(C(I)=C1)=O)NC2=NC=C(C3=CC=CC=C3)C=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
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Topics Palmitoylation: Bridging Physiology and Disease
Palmitoylation is a reversible lipid modification in which palmitate is covalently attached to protein cysteine residues, thereby regulating protein localization, stability, membrane association, and signaling activity.
2026-06-18
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
WHN-88 関連分類
HY-164547 関連分類
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