KIF18A-IN-15
KIF18A-IN-15 (Compound Example 36) is a KIF18A inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, with IC50s of 0.01-0.1 μM, respectively. EX36-A and EX36-B inhibit OVCAR-3 cells viability with IC50s of 0.01-0.1 μM and 0-0.01 μM, respectively. KIF18A-IN-15 can be used in tumor (e.g. colon, breast, lung) studies.
For research use only. We do not sell to patients.
- CAS No.: 3051552-64-5
- Formula: C25H33F3N6O5S
- Molecular Weight:586.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Kinesin Isoforms
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Biological Activity
EX36-A and EX36-B inhibit OVCAR-3 cells viability with IC50s of 0.01-0.1 μM and 0-0.01 μM, respectively. [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3051552-64-5
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Molecular Weight 586.63
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Formula C25H33F3N6O5S
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SMILES
O=C1NC2=CC(C)=N/C(N2)=N/CC(COCC3(C(F)(F)F)CCN(CC3)C4=CC(NS(=O)(CCO)=O)=CC=C14)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)