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Cat. No.: HY-N20636

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7α-Morroniside

7α-Morroniside is a STAT3 promoter inhibitor. 7α-Morroniside inhibits IL-6-induced STAT3 promoter activity in hepatocellular carcinoma cells. 7α-Morroniside can be used for the research of inflammation-related diseases.

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CAS No.: 61849-88-5
화학식: C₁₇H₂₆O₁₁
분자량:406.38

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

7α-Morroniside Chemical Structure

CAS No.: 61849-88-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
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Calculators
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Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

STAT3

All STAT Isoforms :

In Vitro

7α-Morroniside (Compound 22) (7 μM; 1 h pre-incubation + 6 h co-incubation with IL-6) potently inhibits IL-6-induced STAT3 promoter activity in HepG2 cells, with an IC₅₀ of 7 μM, and shows no cytotoxicity at effective concentrations^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 61849-88-5
분자량 406.38
화학식 C₁₇H₂₆O₁₁
SMILES

COC(C1=CO[C@H]([C@@]2([H])[C@]1([H])C[C@H](O[C@H]2C)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Ye XS, et al.. Cornusides A-O, Bioactive Iridoid Glucoside Dimers from the Fruit of Cornus officinalis. Journal of natural products. 2017 Dec 22;80(12):3103-3111. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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7α-Morroniside

All STAT Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

7α-Morroniside Related Classifications

HY-N20636 Related Classifications