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Cat. No.: HY-150266

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A-1293102

A-1293102 is a potent and selective BCL-XL inhibitor that kills BCL-XL-dependent tumor cells.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1565759-96-7
화학식: C₄₂H₄₀F₃N₇O₇S₅
분자량:972.13

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

A-1293102 Chemical Structure

CAS No.: 1565759-96-7

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

A-1293102 is a potent and selective BCL-XL inhibitor that kills BCL-XL-dependent tumor cells^[1].

All Bcl-2 Family Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
MOLT-4	EC₅₀	0.08 μM Compound: 4; A-1293102	Cytotoxicity against human MOLT-4 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay Cytotoxicity against human MOLT-4 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay	[PMID: 34141086]
RS4-11	EC₅₀	>5 μM Compound: 4; A-1293102	Cytotoxicity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay Cytotoxicity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay	[PMID: 34141086]

Chemical Information

CAS No. 1565759-96-7
분자량 972.13
화학식 C₄₂H₄₀F₃N₇O₇S₅
SMILES

O=C(C1=C2C(CCN(C3=NC(C(NS(=O)(C4=CC(S(C(F)(F)F)(=O)=O)=C(C=C4)N[C@@H](CSC5=CC=CC=C5)CCN6CCOCC6)=O)=O)=CS3)C2)=CC=C1)NC7=NC8=CC=CC=C8S7
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhi-Fu Tao, et al.Structure-Based Design of A-1293102, a Potent and Selective BCL-XL Inhibitor. ACS Medicinal Chemistry Letters 2021 12 (6), 1011-1016.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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