Acetylcholine bromide
Based on 28 publication(s) in Google Scholar
Acetylcholine bromide is an organic choline salt compound commonly used in neurophysiology and pharmacology experiments. It plays an important role in the nervous system, acting as a neurotransmitter that transmits signals and regulates many important physiological functions. Due to its special biological activity, Acetylcholine bromide is widely used in the study of neurotransmitters, nerve damage and muscle movement.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.02%
- CAS No.: 66-23-9
- 화학식: C7H16BrNO2
- 분자량:226.11
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보관:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Acetylcholine bromide
More- Cancer Cell. 2025 Aug 12:S1535-6108(25)00330-7. [Abstract]
- Cell. 2026 Mar 5;189(5):1323-1340.e25. [Abstract]
- Cell Res. 2026 Apr;36(4):286-299. [Abstract]
- Trends Biotechnol. 2025 Apr;43(4):918-945. [Abstract]
- Redox Biol. 2024 Feb:69:103004. [Abstract]
- MedComm (2020). 2026 Mar 28;7(4):e70706. [Abstract]
- Phytomedicine. 2026 Jan 17:153:157846. [Abstract]
- J Hazard Mater. 2024 Sep 5:479:135690. [Abstract]
- J Hazard Mater. 2024 Mar 5:465:133248. [Abstract]
- Acta Pharmacol Sin. 2025 Mar 26. [Abstract]
- Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2402143121. [Abstract]
- Curr Biol. 2026 May 4;36(9):2367-2381.e9. [Abstract]
- J Ethnopharmacol. 2024 Aug 22:118707. [Abstract]
- Mol Metab. 2026 May 26:102384. [Abstract]
- Mol Metab. 2023 Dec:78:101811. [Abstract]
- Cells. 2024 Oct 14;13(20):1697. [Abstract]
- Int J Mol Sci. 2026 Apr 9;27(8):3381. [Abstract]
- Biochim Biophys Acta Mol Basis Dis. 2024 Aug 30:167488. [Abstract]
- ACS Pharmacol Transl Sci. 2025 Jun 6;8(7):2048-2060. [Abstract]
- Mol Cell Endocrinol. 2025 Jan 21:599:112464. [Abstract]
- BMC Pulm Med. 2021 Jun 5;21(1):189. [Abstract]
- Front Cardiovasc Med. 2021 Jun 16:8:679240. [Abstract]
- Clin Exp Pharmacol Physiol. 2025 Nov;52(11):e70081. [Abstract]
- Turk J Med Sci. 2025 Feb 19;55(2):509-517. [Abstract]
- UCSF. 2025.
- Res Sq. 2025 Nov 12.
- Biomed Pharmacother. 2024 Jul 12:177:117105. [Abstract]
- bioRxiv. 2023 Oct 13.
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In Vivo Efficacy Study
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IF
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Flow Cytometry
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In Vivo Efficacy Study
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Cell Proliferation/Viability Assay
Biological Activity
Acetylcholine (bromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 66-23-9
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Appearance Solid
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분자량 226.11
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화학식 C7H16BrNO2
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Color White to light yellow
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SMILES
O=C(OCC[N+](C)(C)C)C.[Br-]
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Synonyms
ACh bromide
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (28)
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Journal Impact Factor
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Most Recent
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Cancer Cell
2025 Aug 12:S1535-6108(25)00330-7. PMID: 40829591 -
Cell
Sympathetic-epithelial crosstalk governs tissue-resident memory T cell immunosurveillance in the skin. [Abstract]2026 Mar 5;189(5):1323-1340.e25. PMID: 41616781 -
Cell Res
Light sensing enhances thermotolerance and competitive fitness via serotonergic signaling in an eyeless organism. [Abstract]2026 Apr;36(4):286-299. PMID: 41764323 -
Trends Biotechnol
Programmable embedded bioprinting for one-step manufacturing of arterial models with customized contractile and metabolic functions. [Abstract]2025 Apr;43(4):918-945. PMID: 39779422 -
Redox Biol
Myeloid ACE2 protects against septic hypotension and vascular dysfunction through Ang-(1-7)-Mas-mediated macrophage polarization. [Abstract]2024 Feb:69:103004. PMID: 38141575 -
MedComm (2020)
2026 Mar 28;7(4):e70706. PMID: 41930327 -
Phytomedicine
Andrographolide ameliorates vascular injury in hypertension by suppressing EndMT via Sp1-Notch1 signaling. [Abstract]2026 Jan 17:153:157846. PMID: 41653618 -
J Hazard Mater
β-ionone inhibits the grazing of Daphnia sinensis by reducing the activity of acetylcholinesterase. [Abstract]2024 Sep 5:479:135690. PMID: 39255669 -
J Hazard Mater
β-cyclocitral, a novel AChE inhibitor, contributes to the defense of Microcystis aeruginosa against Daphnia grazing. [Abstract]2024 Mar 5:465:133248. PMID: 38147752 -
Acta Pharmacol Sin
Huperzine A attenuates epileptic seizures via enhancing dCA1-projecting septal cholinergic transmission. [Abstract]2025 Mar 26. PMID: 40140526
Acetylcholine bromide purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2025 Mar 26. [Abstract]
Acetylcholine (ACh, 20 μM; 250 nL, locally injected into the dorsal CA1 (dCA1)). AAV-EF1α-FLEX-taCasp3 virus was injected in the medial septum (MS) and the cannula was implanted in the dCA1 for Hup A (0.1 -1 mg/kg; i.p.) intervention. Effects of Hup A on the development of seizure stage (Left) and ADDs (Right) during kindling acquisition, in the condition of AAV-taCasp3-mediated apoptosis of the ChAT+ neurons in MS, n=9.
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Proc Natl Acad Sci U S A
2024 Jul 2;121(27):e2402143121. PMID: 38923993
Acetylcholine bromide purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2402143121. [Abstract]
The impact of ACh (Acetylcholine, 1 μM; 24 h) on the uptake of latex beads-rabbit IgG-FITC complex (green) in murine BMDMs (red; Upper) or human MDMs (red; Lower) was assessed. The data are presented as the percentage of latex beads-rabbit IgG-FITC-positive cells relative to the total cell count. (Scale bar, 100 μm.)
Acetylcholine bromide purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2402143121. [Abstract]
BMDMs from ChAT-GFP mice were treated with Pam3, or in combination with ACh (Acetylcholine, 10 μM), for 24 h and subsequently evaluated for GFP expression.
Acetylcholine bromide purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2402143121. [Abstract]
ACh (Acetylcholine, 5 mg/kg; i.p., once daily for 3 days). The number of apoptotic neutrophils was assessed by flow cytometry at day 3 post-Pam3 stimulation in Chatfl/fl and Chatfl/flLyz2cre mice.
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Curr Biol
2026 May 4;36(9):2367-2381.e9. PMID: 42025171 -
J Ethnopharmacol
Mailuoning oral liquid ameliorates vasculitis in thromboangiitis obliterans rats via inactivating cGAS-STING-IRF3 and TLR4-MAPKs/NF-κB signaling pathways. [Abstract]2024 Aug 22:118707. PMID: 39181282 -
Mol Metab
Vagal control of the brain-esophagus axis ameliorates stress-induced esophageal motility dysfunction in male mice. [Abstract]2026 May 26:102384. PMID: 42203107 -
Mol Metab
Deletion of Ascl1 in pancreatic β-cells improves insulin secretion, promotes parasympathetic innervation, and attenuates dedifferentiation during metabolic stress. [Abstract]2023 Dec:78:101811. PMID: 37769990 -
Cells
Single-Cell Hypertrophy Promotes Contractile Function of Cultured Human Airway Smooth Muscle Cells via Piezo1 and YAP Auto-Regulation. [Abstract]2024 Oct 14;13(20):1697. PMID: 39451215 -
Int J Mol Sci
A Clozapine-Responsive GPCR-Based Gene Switch for Pharmacological Control of Gene Expression in Mammalian Cells and In Vivo. [Abstract]2026 Apr 9;27(8):3381. PMID: 42074026 -
Biochim Biophys Acta Mol Basis Dis
Dietary apigenin ameliorates obesity-related hypertension through TRPV4-dependent vasorelaxation and TRPV4-independent adiponectin secretion. [Abstract]2024 Aug 30:167488. PMID: 39218272 -
ACS Pharmacol Transl Sci
Critical Residues in the Gβ Subunit Mediate Selective Recruitment of the Gαq Heterotrimer to Activated G Protein-Coupled Receptors. [Abstract]2025 Jun 6;8(7):2048-2060. PMID: 40672669 -
Mol Cell Endocrinol
Vagotomy suppresses food intake by increasing GLP-1 secretion via the M3 AChR-AMPKα pathway in mice. [Abstract]2025 Jan 21:599:112464. PMID: 39848433 -
BMC Pulm Med
Opposing responses of the rat pulmonary artery and vein to phenylephrine and other agents in vitro. [Abstract]2021 Jun 5;21(1):189. PMID: 34090386 -
Front Cardiovasc Med
2021 Jun 16:8:679240. PMID: 34222374 -
Clin Exp Pharmacol Physiol
Indole-3-Propionic Acid Improves Vascular Function in High-Fat Diet-Induced Obese Mice via eNOS. [Abstract]2025 Nov;52(11):e70081. PMID: 41057979 -
Turk J Med Sci
2025 Feb 19;55(2):509-517. PMID: 40342326 -
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Biomed Pharmacother
Spinosad blocks CHRNA5 mediated EGFR signaling pathway activation to inhibit lung adenocarcinoma proliferation. [Abstract]2024 Jul 12:177:117105. PMID: 39002438
Acetylcholine bromide purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jul 12:177:117105. [Abstract]
The addition of exogenous Acetylcholine (1-10 μM) reversed the decline in H1975 cell viability induced by Spinosad (10 μM).
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용액&용해도
H2O : 250 mg/mL (1105.66 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (244 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.4226 mL | 22.1131 mL | 44.2263 mL | 110.5657 mL |
| 5 mM | 0.8845 mL | 4.4226 mL | 8.8453 mL | 22.1131 mL | |
| 10 mM | 0.4423 mL | 2.2113 mL | 4.4226 mL | 11.0566 mL | |
| 15 mM | 0.2948 mL | 1.4742 mL | 2.9484 mL | 7.3710 mL | |
| 20 mM | 0.2211 mL | 1.1057 mL | 2.2113 mL | 5.5283 mL | |
| 25 mM | 0.1769 mL | 0.8845 mL | 1.7691 mL | 4.4226 mL | |
| 30 mM | 0.1474 mL | 0.7371 mL | 1.4742 mL | 3.6855 mL | |
| 40 mM | 0.1106 mL | 0.5528 mL | 1.1057 mL | 2.7641 mL | |
| 50 mM | 0.0885 mL | 0.4423 mL | 0.8845 mL | 2.2113 mL | |
| 60 mM | 0.0737 mL | 0.3686 mL | 0.7371 mL | 1.8428 mL | |
| 80 mM | 0.0553 mL | 0.2764 mL | 0.5528 mL | 1.3821 mL | |
| 100 mM | 0.0442 mL | 0.2211 mL | 0.4423 mL | 1.1057 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.