Amilo-5MER
Based on 1 publication(s) in Google Scholar
Amilo-5MER (5-MP) is an orally active and selective Serum Amyloid A (SAA) inhibitor. Amilo-5MER specifically inhibits the release of pro-inflammatory cytokines IL-6 and IL-1β from SAA-activated cells. Amilo-5MER reduces chronic inflammation and relieves symptoms of diseases such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and multiple sclerosis (MS). Amilo-5MER is promising for research of autoimmune diseases and chronic inflammatory diseases.
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- CAS No.: 1860001-61-1
- 화학식: C23H40N6O9S
- 분자량:576.66
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Amilo-5MER
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Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1860001-61-1
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분자량 576.66
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화학식 C23H40N6O9S
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Synonyms
5-MP
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Sequence
Ac-Met-Thr-Ala-Asp-Val-NH2
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Sequence Shortening
Ac-MTADV-NH2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury. [Abstract]2026 Jun;13(34):e22891. PMID: 41904943
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)