Cyetpyrafen
Cyetpyrafen is a pyrazole insecticide/acaricide with broad-spectrum insecticidal activity. Cyetpyrafen binds to DhelOBP4 (Ki = 4.95 μM) and DhelOBP21 (Ki = 5.51 μM) to mediate olfactory recognition in *Cryptolaemus montrouzieri*. Cyetpyrafen induces dose-dependent electroantennogram responses in *Cryptolaemus montrouzieri* and exhibits repellent effects on the species. Cyetpyrafen has bioaccumulative properties, is rapidly and passively absorbed by the roots of lettuce and rice, reaches a steady state within 24 h, preferentially accumulates in roots, and shows limited xylem/phloem translocation.
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- CAS No.: 1253429-01-4
- 화학식: C24H31N3O2
- 분자량:393.53
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
제품 설명
In Vitro
Cyetpyrafen (1.12 mg/L; 1-96 h) is rapidly taken up by Oryza sativa (rice) and Lactuca sativa (lettuce) roots, reaching steady state within 24 h, with preferential accumulation in roots (average RCFs 1290 mL/g for rice, 1730 mL/g for lettuce) and poor translocation to shoots, and is eliminated more slowly from lettuce roots than rice roots[2].
Cyetpyrafen (5 mg/L; 3-96 h) does not undergo phloem-mediated translocation in Oryza sativa seedlings, as it cannot migrate from exposed roots to unexposed roots or shoots[2].
Cyetpyrafen (1.12 mg/L; 24-96 h) exposure induces significant increases in the activities of CYP450, POD, CarE, GT, and GST in rice and lettuce roots, indicating these enzymes mediate the metabolic transformation of cyetpyrafen in plants[2].
Cyetpyrafen is predicted to be very toxic to fish and highly toxic to daphnid and green algae, with several of its phase I metabolites (M-391, M-409-1/2, M-407) exhibiting similar ecotoxicity levels, while phase II metabolites show reduced toxicity[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1253429-01-4
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분자량 393.53
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화학식 C24H31N3O2
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SMILES
C(=C(\C#N)/C1=CC=C(C(C)(C)C)C=C1)(\OC(C(C)(C)C)=O)/C=2N(CC)N=C(C)C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Mao Z, et al. Cyetpyrafen, chlorfenapyr and spirodiclofen affect the olfactory recognition of Dastarcus helophoroides by acting on DhelOBP4 and DhelOBP21. Pestic Biochem Physiol. 2025;214:106568. [Content Brief]
[2]. Li R, et al. Insight into the uptake and metabolism of a new insecticide cyetpyrafen in plants. Environ Int. 2022;169:107522. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)