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Cat. No.: HY-402601

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Desethyl-SID 7969543

고객리뷰

Based on 1 Customer Validation

Desethyl-SID 7969543 is an isoquinolinone analog of SID 7969543 (HY-107404) and a selective SF-1 (NR5A1) inhibitor. Desethyl-SID 7969543 shows no activity against RORA, VP16 and LRH-1, and exhibits no cytotoxicity at concentrations close to its SF-1 IC₅₀ value.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity: 98.83%
화학식: C₂₂H₂₀N₂O₇
분자량:424.40

보관:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Desethyl-SID 7969543 Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

RORα

All ROR Isoforms :

Chemical Information

Appearance Solid
분자량 424.40
화학식 C₂₂H₂₀N₂O₇
Color White to off-white
SMILES

O=C1C2=CC=CC(OC(C)C(O)=O)=C2C=CN1CC(NC3=CC4=C(C=C3)OCCO4)=O
선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Madoux F, et al. Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening[J]. Molecular pharmacology, 2008, 73(6): 1776-1784.

[2]. Roth J, et al. Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds. Bioorg Med Chem Lett. 2008;18(8):2628-2632. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

견적 받기 해외재고보유

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

Desethyl-SID 7969543

Metabolism/Protease Compound Library

Small Molecule Immuno-Oncology Compound Library

Transcription Factor-Targeted Library

Nuclear Receptor Compound Library

Metabolic Enzyme Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Protein Kinase Compound Library

High-Throughput Bioactive Compound Library

All ROR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Desethyl-SID 7969543

Metabolism/Protease Compound Library

Small Molecule Immuno-Oncology Compound Library

Transcription Factor-Targeted Library

Nuclear Receptor Compound Library

Metabolic Enzyme Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Protein Kinase Compound Library

High-Throughput Bioactive Compound Library

All ROR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Desethyl-SID 7969543 Related Classifications

HY-402601 Related Classifications