F3 peptide

F3 peptide is a nucleolin-binding tumor-homing peptide that mediates selective uptake and internalization by tumor cells. F3 peptide is a 31-amino acid fragment of human high mobility group nucleosomal protein 2 (HMGN2). F3 peptide inhibits protein synthesis through ribosome inactivation. F3 peptide targets the tumor vasculature. F3 peptide can serve as an effective ligand to improve the druggability of macromolecular drugs or nanoparticles. F3 peptide is used in research on cancers such as glioblastoma and breast cancer.

• Data Sheet (280 KB)
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