HDAC-IN-72
HDAC-IN-72 (compound 7j) is the most potent HDAC1 (IC50=0.65 μM), HDAC2 (IC50=0.78 μM), HDAC3 (IC50=1.70 μM) inhibitor and antiproliferative compound. HDAC-IN-72 can be used for breast cancer research.
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- CAS No.: 763066-77-9
- 화학식: C22H21N3O2
- 분자량:359.42
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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HDAC1 0.65 μM (IC50) |
HDAC2 0.78 μM (IC50) |
HDAC3 1.70 μM (IC50) |
HDAC-IN-72 (0.1-50 μM, 48 h) shows good anti-proliferative activity against MCF-7 (IC50=0.83±1.41 μM) and T47D (IC50=1.4±1.85 μM) cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 763066-77-9
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분자량 359.42
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화학식 C22H21N3O2
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SMILES
O=C(NCC1=CC=C(C(NC2=CC=CC=C2N)=O)C=C1)C3=CC=C(C)C=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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