Idroxioleic acid
Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities.
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- CAS No.: 182370-45-2
- 화학식: C18H34O3
- 분자량:298.46
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) inhibited the growth of A549, lung adenocarcinoma cell line with an IC50 of 252 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male NUDE (Swiss) Crl:NU(Ico)-Foxn1nu mice (5 weeks old, 30-35 g) injected with A549 human lung cancer cells[1]
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Dosage:400 mg/kg
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Administration:p.o.; daily; for 21 days
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Result:Caused a reduction in tumor volume of about 20-25% after 21 days.
Chemical Information
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CAS No. 182370-45-2
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분자량 298.46
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화학식 C18H34O3
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SMILES
OC([C@H](O)CCCCCC/C=C\CCCCCCCC)=O
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Synonyms
(R)-2-Hydroxyoleic acid; (R)-2-OHOA; (R)-LAM561
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Idroxioleic acid Related Classifications
HY-139784 Related Classifications
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