iHAC
iHAC is an inhibitor HSP90-anchoring chimera, that covalently binds BRD4 ligand (+)-JQ-1 to HSP90, and inhibits the proliferation of cancer cells. iHAC activates the anti-tumor immune response, inhibits the recurrence and metastasis of 4T1 breast cancer in mouse models.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C50H46ClIN16O7S3
- 분자량:1241.56
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
분자량 1241.56
-
화학식 C50H46ClIN16O7S3
-
SMILES
ClC1=CC=C(C2=N[C@@H](CC(NCC3=CN(CCCC(N(CC#N)S(=O)(C4=CC=C(C(NCCCN5C(SC6=CC(OCO7)=C7C=C6I)=NC8=C(N)N=CN=C85)=O)C=C4)=O)=O)N=N3)=O)C9=NN=C(C)N9C%10=C2C(C)=C(C)S%10)C=C1
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)