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Cat. No.: HY-116610

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L 748780

L 748780 (compound 2) is a selectivity COX-2 inhibitor with the IC₅₀ values of 0.5 μM and ＞ 100 μM for COX-2 and COX-1, respectively.

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CAS No.: 168086-64-4
화학식: C₁₉H₁₄Cl₃NO₄
분자량:426.68

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

L 748780 Chemical Structure

CAS No.: 168086-64-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

L 748780 (compound 2) is a selectivity COX-2 inhibitor with the IC₅₀ values of 0.5 μM and ＞ 100 μM for COX-2 and COX-1, respectively^[1].

IC₅₀ & Target

COX-2

0.5 μM (IC₅₀)

COX-1

> 100 μM (IC₅₀)

All COX Isoforms :

Chemical Information

CAS No. 168086-64-4
분자량 426.68
화학식 C₁₉H₁₄Cl₃NO₄
SMILES

O=C(CC1=C(C)N(C(C2=C(Cl)C=C(Cl)C=C2Cl)=O)C3=C1C=C(C=C3)OC)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lau CK, et al. From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors. Adv Exp Med Biol. 1997;407:73-8. PMID: 9321934. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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L 748780

All COX Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

L 748780 Related Classifications

HY-116610 Related Classifications