Copy Link Print Information

MPP+ iodide

37 Cited Publications
고객리뷰

Based on 37 publication(s) in Google Scholar

MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • Purity: 99.96%
  • CAS No.: 36913-39-0
  • 화학식: C12H12IN
  • 분자량:297.14
  • 보관:

    4°C, sealed storage, away from moisture and light

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

  • MPP+ iodide Chemical Structure
    MPP+ iodide Chemical Structure
  • Experimental Validation Results for MPP+ iodide
  • Experimental Validation Results for MPP+ iodide
  • Experimental Validation Results for MPP+ iodide
  • Experimental Validation Results for MPP+ iodide
  • Experimental Validation Results for MPP+ iodide
  • Experimental Validation Results for MPP+ iodide
  • Experimental Validation Results for MPP+ iodide
CAS No.: 36913-39-0
사이즈
가격
재고
수량
Amount: USD 0.00
Please select quantity
or
or

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of MPP+ iodide:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • 용액&용해도
  • 순도&문서
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) MPP+ iodide

More
Customer Validation & Images
Cell Proliferation/Viability AssayCell Imaging/StainingApoptosis AnalysisFlow CytometryWB
  • Cell Imaging/Staining
  • Apoptosis Analysis
  • Flow Cytometry
  • Cell Proliferation/Viability Assay
  • Cell Imaging/Staining
  • Cell Proliferation/Viability Assay
  • WB
Keywords
MOQ
Minimum order quantity
100 mg

견적 받기 해외재고보유

Other size
견적 받기
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress 로그인
Register
Sign in to MedChemExpress
회원가입

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • MPP+ iodide Chemical Structure
    MPP+ iodide Chemical Structure
    1/16
  • 1/16

    MPP+ iodide purchased from MedChemExpress. Usage Cited in: Cell Death Discov. 2025 Jul 29;11(1):351. [Abstract]

    Customer Validation
     SH-SY5Y cells were treated for 24 h with 1 μM MPP (MPP+ iodide). Bright field images of cells in the PD cell model.

  • 1/16

    MPP+ iodide purchased from MedChemExpress. Usage Cited in: Cell Death Discov. 2025 Jul 29;11(1):351. [Abstract]

    Customer Validation
     SH-SY5Y cells were treated for 24 h with 1 μM MPP (MPP+ iodide). Representative images (left) and ratios (right) of TUNEL+ cells in PD cell model.

  • 1/16

    MPP+ iodide purchased from MedChemExpress. Usage Cited in: Cell Death Discov. 2025 Jul 29;11(1):351. [Abstract]

    Customer Validation
     SH-SY5Y cells were treated for 24 h with 1 μM MPP (MPP+ iodide). Representative images of flow cytometric analysis of MMP in PD cell model (left), median fluorescence intensity (MFI; middle), and the proportion of high MMP (H-MMP) to total cell number (right).

  • 1/16

    MPP+ iodide purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2024 Nov 10;22(1):690. [Abstract]

    Customer Validation
     CCK8 assay of SH-SY5Y cells treated with MPP+ (MPP+ iodide, 1 mM; 24 h) and purified melanin.

  • 1/16

    MPP+ iodide purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2024 Nov 10;22(1):690. [Abstract]

    Customer Validation
     Typical JC-1 staining (Left) and TMRE staining (Right) of MPP+- (MPP+ iodide, 1 mM , 12 h) treated SH-SY5Y cells that were co-cultured with E. coli with distinct pretreatments.

  • 1/16

    MPP+ iodide purchased from MedChemExpress. Usage Cited in: Neurochem Res. 2023 Jul;48(7):2129-2137. [Abstract]

    Customer Validation
     MPP+ iodide (MPP+; 0, 0.2, 0.4, 0.6, 0.8, 1, 2 mM; 48 h) decreases viability of SH-SY5Y cells (Fig D). At a concentration of 0.6 mM, MPP+ iodide decreases the cell viability by 25%. Moreover, the IC50 value of MPP+ iodide on SH-SY5Y cells is 1.233 mM (Fig C).

  • 1/16

    MPP+ iodide purchased from MedChemExpress. Usage Cited in: Neurochem Res. 2023 Jul;48(7):2129-2137. [Abstract]

    Customer Validation
     MPP+ iodide (MPP+; 1.2 mM; 48 h) decreases TH, Prdx-2, SIRT1 protein levels and increases the ratio of Bax / Bcl-2, in SH-SY5Y cells.

  • MPP+ iodide