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MSAB

56 Cited Publications
고객리뷰

Based on 56 publication(s) in Google Scholar

MSAB is a potent and selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin and promotes its degradation, and specifically downregulates Wnt/β-catenin target genes. MSAB exhibits potent anti-tumor effects selectively on Wnt-dependent cancer cells.

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  • Purity: 99.77%
  • CAS No.: 173436-66-3
  • 화학식: C15H15NO4S
  • 분자량:305.35
  • 보관:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 2 years , -20°C, 1 year
  • MSAB Chemical Structure
    MSAB Chemical Structure
  • Experimental Validation Results for MSAB
  • Experimental Validation Results for MSAB
  • Experimental Validation Results for MSAB
  • Experimental Validation Results for MSAB
  • Experimental Validation Results for MSAB
CAS No.: 173436-66-3
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  • MSAB Chemical Structure
    MSAB Chemical Structure
    1/16
  • 1/16

    MSAB purchased from MedChemExpress. Usage Cited in: Exploration. 2025 Jun 08.

    Customer Validation
     Quantitative assessment of the impact of MSAB (10 μM; 48 h) on the RL-QN15-induced hESCs proliferation and viability.

  • 1/16

    MSAB purchased from MedChemExpress. Usage Cited in: Exploration. 2025 Jun 08.

    Customer Validation
     Representative images demonstrate the effectiveness of RL-QN15 in repairing hESC scratches with and without MSAB (10 μM; 0–48 h).

  • 1/16

    MSAB purchased from MedChemExpress. Usage Cited in: Exploration. 2025 Jun 08.

    Customer Validation
     Effect of MSAB (10 μM; 72 h) on the expression of the proliferation-related stemness-related protein CK19 in hESCs treated with 10 nM RL-QN15. GAPDH was used as an internal control.

  • 1/16

    MSAB purchased from MedChemExpress. Usage Cited in: J Adv Res. 2025 Apr 27:S2090-1232(25)00282-6. [Abstract]

    Customer Validation
     HE staining images of skin wound tissue with MSAB (20 mg/kg, ip, every two days for two weeks).

  • 1/16

    MSAB purchased from MedChemExpress. Usage Cited in: Cancers (Basel). 2023 Mar 16;15(6):1801. [Abstract]

    Customer Validation
     MSAB (5 μM) attenuates the activity of Wnt3a and β-caten in SiHa cells.

  • MSAB