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Cat. No.: HY-116259

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PT-S58

PT-S58, a GSK0660 derivative, is a PPARβ/δ full antagonist with an IC₅₀ value of 98 nM. PT-S58 inhibits the agonist-induced transcriptional activity of PPARβ/δ in vitro.

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CAS No.: 1356497-92-1
화학식: C₁₇H₂₂N₂O₅S₂
분자량:398.50

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

PT-S58 Chemical Structure

CAS No.: 1356497-92-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

PT-S58, a GSK0660 derivative, is a PPARβ/δ full antagonist with an IC₅₀ value of 98 nM. PT-S58 inhibits the agonist-induced transcriptional activity of PPARβ/δ in vitro^[1].

IC₅₀ & Target^[1]

PPARβ/δ

98 nM (IC₅₀)

All PPAR Isoforms :

Chemical Information

CAS No. 1356497-92-1
분자량 398.50
화학식 C₁₇H₂₂N₂O₅S₂
SMILES

O=C(C1=C(S(=O)(NC2=CC=C(NC(C)(C)C)C=C2OC)=O)C=CS1)OC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Naruhn S, et al. High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties. Mol Pharmacol. 2011 Nov;80(5):828-38. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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PT-S58

All PPAR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PT-S58 Related Classifications

HY-116259 Related Classifications