PY-PAP
PY-PAP is a photoactivatable affinity probe and a derivative of PY-60 (HY-141644). PY-PAP retains the cellular function of activating YAP transcriptional activity. In 293A cells, PY-PAP can label cathepsin D (CTSD) and annexin A2 (ANXA2) through ultraviolet crosslinking and click reactions. PY-PAP plays a key role in identifying ANXA2 as the specific target of PY-60.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2765218-57-1
- 화학식: C25H30N6O3
- 분자량:462.54
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All YAP Isoforms
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Biological Activity
제품 설명
Chemical Information
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CAS No. 2765218-57-1
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분자량 462.54
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화학식 C25H30N6O3
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SMILES
O=C(C1=NOC(C2=CC=CC=C2)=C1)NCCCN3CCN(CC3)C(CCC4(CCC#C)N=N4)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Dual Luciferin reporter gene assay
Luciferin reporter gene assay is a reporting system to detect the activity of Firefly Luciferase using luciferin as a substrate, which is often used in the research of miRNA target gene verification and promoter transcriptive activity regulation. Dual luciferase usually refers to Firefly luciferase and Renilla luciferase.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)