Soporidine
Soporidine is an antagonist of germination of the parasitic plant Striga hermonthica. Soporidine specifically inhibits a S. hermonthica strigolactone receptor and inhibits the parasite's germination. Soporidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- CAS No.: 1060376-43-3
- 화학식: C27H30F3NO3
- 분자량:473.53
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
More
Biological Activity
제품 설명
In Vitro
Soporidine binds to the AtHTL receptor and to a key Strigolactone (SL) receptor in S. hermonthica, inhibiting Striga germination in the presence of SLs. Soporidine could serve as the basis for the development of Strigolactone (SL) antagonist to combat Striga infestations. Soporidine is a potent antagonist in GR24-dependent Arabidopsis germination assay and shows no enhancement of SL signaling mutant phenotypes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1060376-43-3
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분자량 473.53
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화학식 C27H30F3NO3
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SMILES
O=C(OCC)C1(CCN(CC1)CC2=CC=C(C=C2)C#CCCO)CC3=CC=CC(C(F)(F)F)=C3
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Synonyms
RG4; SOP
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)