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Cat. No.: HY-176488

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Y-99

Y-99 is a PORCN inhibitor with an IC₅₀ of 155.4 nM against the Wnt/β-catenin signaling pathway. Y-99 inhibits the expression of p-LRP6, β-catenin, and c-Myc.

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CAS No.: 2034334-74-0
화학식: C₁₈H₁₇F₂N₅O₃
분자량:389.36

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Y-99 Chemical Structure

CAS No.: 2034334-74-0

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Y-99 is a PORCN inhibitor with an IC₅₀ of 155.4 nM against the Wnt/β-catenin signaling pathway. Y-99 inhibits the expression of p-LRP6, β-catenin, and c-Myc^[1].

All Wnt Isoforms :

Chemical Information

CAS No. 2034334-74-0
분자량 389.36
화학식 C₁₈H₁₇F₂N₅O₃
SMILES

O=C(NCC1=NC(C2CCC(F)(F)CC2)=NO1)C3=NOC(C4=CC=CN=C4)=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yang X, et al. Discovery and Identification of a Novel PORCN Inhibitor via Structure-Based Virtual Screening. ACS Chem Biol. 2025 Jun 20;20(6):1319-1332. [Content Brief]

Calculators

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Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
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수량:
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Y-99

All Wnt Isoforms