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Cat. No.: HY-135865

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KRAS inhibitor-7

KRAS inhibitor-7 is a potent KRAS G12C inhibitor, extracted from patent WO2017087528A1, compound B.

For research use only. We do not sell to patients.

CAS No.: 2022986-68-9
Formula: C₂₆H₂₇ClF₂N₆O₂
Molecular Weight:528.98

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

KRAS inhibitor-7 Chemical Structure

CAS No.: 2022986-68-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

KRAS inhibitor-7 is a potent KRAS G12C inhibitor, extracted from patent WO2017087528A1, compound B^[1].

IC₅₀ & Target^[1]

KRAS(G12C)

All Ras Isoforms :

Chemical Information

CAS No. 2022986-68-9
Molecular Weight 528.98
Formula C₂₆H₂₇ClF₂N₆O₂
SMILES

C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(F)C=CC=C4O)=C(F)C3=NC(N5CC(N(C)C)C5)=N2)CC1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liansheng Li, et al. 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof. WO2017087528A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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KRAS inhibitor-7

All Ras Isoforms